Archeological evidence suggests that Neanderthals might have been aware of the medicinal properties of plants over 60,000 years ago. Imagine you are a modern-day ethnobotanist and have identified a compound from fossilized tree pollen that binds to the alpha subunit of the most common G-proteins. To test how whether the compound affects the activity of Gα, you treat liver cells with the compound alongside epinephrine. You observe that the cells fail to produce glucose. Which could be the activity of the compound?

Answers

Answer 1

Answer:

It could be prevent Ga from binding to the epinephrine receptor.

Explanation:

Hindering GTPase action will make G-protein to tie to adenyl cyclase for all time so Glucose is delivered persistently.  

Diminishing the proclivity for GDP will build the opportunity of authoritative of GTP to G protein which thus will initiate the pathway.  

On the off chance that G protein ties with adenyl cyclase it will invigorate it.  

Yet, in the event that the G-protein is kept from official with epinephrine receptor, at that point the receptor can't enact trade the guanine nucleotide to G-protein for initiation. Thus the G-protein stays in latent state.

Answer 2

The activity of the compound should be that  It could prevent Ga from binding to the epinephrine receptor.

How to make G-protein:

In the case when GTPase activity should be inhibiting for binding the adenyl cyclase in a permanent way due to this the glucose should be generated in a continuous way. In the case when it reduced the affinity for GDP it raised the chance of binding for GTP to G protein that turned the activation of the pathway.  

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Related Questions

Both crystal violet and safranin are basic stains and may be used to do simple stains on Gram-positive and Gram-negative cells. This being the case, explain how they end up staining Gram-positive and Gram-negative cells differently in the Gram stain.

Answers

Answer:

Gram positive cells retains purple stains of crystal violet, gram-negative cells takes up red or pink stain of safranin

Explanation:

Gram staining is a simple method of distinguishing between Gram-positive cells and Gram-negative cells. The method make use of the following steps

Heat fix cells on a glass slide and then:

1. Stain cell with crystal violet for 1 min

2. Rinse with water

3. Decolourize with alcohol for 30 seconds and wash with water

4. flood cells with iodine as mordant

5. Flush with water

6. Counterstain with safranin for 1 min and wash with water

7. View under the microscope

Gram-positive cell possesses a thick peptidoglycan in its cell wall which helps retain the purple colour of the crystal violet, While Gram-negative cells will loose out this colour when flushed with alcohol but takes up the red or pink colour when stained with safranin.

Final answer:

Crystal violet stains Gram-positive cells purple, while safranin stains Gram-negative cells pink in the Gram stain.

Explanation:

Crystal violet and safranin are used in the Gram stain to differentiate between Gram-positive and Gram-negative cells. Crystal violet is a primary stain that binds to the thick peptidoglycan layer of Gram-positive cells, making them appear purple.

Safranin, a secondary counterstain, is applied after decolorization and stains the decolorized Gram-negative cells pink. The differences in cell wall structure and the interaction of the stains with the cell walls result in the differential staining of Gram-positive and Gram-negative cells.

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In cattle, coats may be solid white, solid black, or black-and-white spotted. When true-breeding solid whites are mated with true-breeding solid blacks, the F1 generation consists of all solid white individuals. After many F1×F1 matings, the following ratio was observed in the F2 generation: 12/16 solid white 3/16 black-and-white spotted 1/16 solid black Part A How many gene pairs are involved in the inheritance of cattle coat color?

Answers

Answer:

Two locus

Explanation:

Let assume  the gene for white (1st locus) be W i.e. ww = recessive

here, Let the alleles for the 2nd locus be B and b.

White: W_B_, W_bb

Black&White: wwB_

Black: wwbb

This is dominant epistasis. In dominant epistasis, where the dominant allele of the 1st locus (W) masks or hide the expression of the 2nd locus. When the two alleles in the 1st locus are recessive (ww), the alleles in the 2nd locus can be expressed(B and b).

Two locus gene pairs are involved in the inheritance of cattle coat color

Assumption of Generation:

Let us assume the gene for white (1st locus) be W i.e. ww = recessive here, Let the alleles for the 2nd locus be B and b.

White: W_B_, W_bbBlack&

White: wwB_Black: wwbb

This represents dominant epistasis. In this, the dominant allele of the 1st locus (W) should mask or hide the expression of the 2nd locus. At the time when the two alleles in the 1st locus are recessive (ww), so the alleles in the 2nd locus could be expressed(B and b).

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in general terms, what two general factors in a medium affect small speed of sound?

Please explain! I will give brainliest!

Answers

Answer:

Density of the medium, temperature of the medium, and stiffness of the medium.

Explanation:

Medium

Medium has a huge effect of the speed of sound.  When most people discuss the “speed of sound” they are talking about the propagation of sound waves through the medium of “Air”.  For anyone who has gone underwater and listen to people talking above it is likely that one would notice the muted an “odd” way that voices sound underwater.  This is because the “medium” of water greatly bends, distorts and changes the speed of sound wave.

There is a whole aspect of science that measure and defines the effect of different mediums (gaseous and liquid) on the speed of sound.  This is called Fluid Dynamics.  Underwater communication is possible if you understand how this wave propagation as well as another important factor (pressure).

Because of elasticity of materials sound will, as a rule of thumb, generally travel faster in solids than in liquids and faster in liquids than in gases.

♦  Temperature

Temperature has a large effect on the speed of sound.  Not as much as the “Medium” does, but far more than anything else.  Temperature affects the speed of sound because temperature can affect the “elastic” qualities of different mediums.  At the very basics lower temperatures will decrease the speed of sound while higher temperatures will increase the speed of sound, all other factors being equal.

♦  Pressure

Pressure is the final factor that has a significant impact on the speed of sound.  The effect of pressure on the speed of sound is due to the materials inertial properties.  In short, the more pressure that is applied to the material or medium the denser it becomes and the greater the “inertia” becomes.  This makes any interactions between particles slower.  Therefore the speed of sound throughout the medium is slowed due to the greater pressure.

Answer:

Elasticity and density

Explanation:

The speed of sound depends on elasticity and density of the medium through which it is travelling. The sound travels faster in liquids than gases. The sound travels faster in solids than in liquids. The lesser the elasticity and higher the density , the sound travels slower in a medium.

Speed = elasticity / density

20. During filtration, which of the following does NOT enter the bowman's capsule from the bloodstream?
A. glucose
B. water
C. ions
D. plasma proteins
E. amino acids

Answers

Answer: option D.

Plasma proteins.

Explanation:

Filtration is the transfer of water and solutes like glucose, ions, amino acids from the plasma to the renal tubules in the renal corpsicule plasma . Renal corpsicule help to filter blood. The fluid present in the blood in the glomerulus is pass to the Bowman's capsule to form glomerular filtrate , plasma protein do not enter Bowman's capsule. The filtrate is processed to form urine in the nephron.

Brain imaging studies have implicated an area of the cortex called the TPO, lying at the junction of the temporal, parietal, and occipital lobes, which may be the cause of this condition:


a. Anesthesia

b. Synesthesia

c. Senesthesia

d. Synosthesia

e. Sensorithesia

Answers

Answer:

B) Synesthesia

Explanation:

Synesthesia is a sensation produced in one modality when a stimulus is applied to another modality, as when the hearing of a certain sound induces the visualization of a certain color. It may be caused by unusual cases of cross-talk between normally separated brain regions. Synesthesia alters connectivity in temporo-occipital and parietal areas. A brain imaging studies that implicated an area of the cortex called the TPO, lying at the junction of the temporal, parietal, and occipital lobes is likely caused by a condition known a synesthesia.

Answer:

Synesthesia

Explanation:

Brain imaging is a relatively new discipline and a breakthrough technology within medicine, neuroscience and psychology used for cognitive neuroscience, behavioral conditioning, and brain science. It involves different techniques(PET,MRI,CT, MRS,MRSI, MEG etc) for image the structure, function, or pharmacology of the nervous system and brain.

Brain imaging studies have implicated an area of the cortex called the TPO, lying at the junction of the temporal, parietal, and occipital lobes, which may be the cause of a condition called Synesthesia

Wikipedia describe Synesthesia as a perceptual phenomenon in which stimulation of one sensory or cognitive pathway leads to involuntary experiences in a second sensory or cognitive pathway i.e crossing of senses.For instance, people with synesthesia may see sounds, tastes word or probably feel a sensation on their skin when they smell certain scents.

Synesthesia forms as either grapheme-color (where letters or numbers are perceived as inherently colred) or number form synethesia

Little is known about how synesthesia develop but through brain imaging studies, it has been implicated that an area of the cortex called the TPO which lies at the junction of the temporal,parietal, and occipital lobes causes synesthesia.

Which of the following processes directly require ATP? Choose all that apply.

a.Diffusion of calcium into the motor neuron at the neuromuscular junction.
b.Release of cross-bridge (interaction) between actin and myosin.
c.Movement of calcium ions back into the sarcoplasmic reticulum after contraction.
d.Conformation change of troponin resulting in the movement of tropomyosin off the actin active sites.

Answers

Answer:the following processes directly require ATP includes:

B (Release of cross-bridge (interaction) between actin and myosin.)

C (Movement of calcium ions back into the sarcoplasmic reticulum after contraction.)

Explanation:

Muscle contraction occurs in various parts of the body to ensure proper body functioning. This process requires the release of calcium ion and the use of ATP ( Adenosine Triphosphate) as source of energy at various levels for the process to take place. The distinct role of ATP in muscle contraction includes:

-ATP is directly required as it causes detachment from actin after power stroke when it binds at one of the reactive sites of myosin. This explains option B (Release of cross-bridge (interaction) between actin and myosin.)

-it powers the pump that transports calcium ions back into the sarcoplasmic reticulum after contraction. This explains option C (Movement of calcium ions back into the sarcoplasmic reticulum after contraction)

- it activates the myosin head so it can bind to actin and rotate by the action of ATpase enzyme.

The following processes which directly require ATP include

Release of cross-bridge (interaction) between actin and myosin.Movement of calcium ions back into the sarcoplasmic reticulum after contraction.

The myosin head has to move in order for the release of cross-bridge

between them to be achieved. The myosin head movement brings about

movement of the actin also.

The movement of calcium also requires the use of ATP as it helps in the

pumping of the calcium ions into the sarcoplasmic reticulum.

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The main purpose of the chloride channel proteins on the apical surface of the intestinal epithelial cells is to create an osmotic gradient that ultimately causes __________ to move through the intestinal epithelium and into the intestinal lumen to assist in the formation of mucus. These are the same chloride channel proteins, adversely affected in cystic fibrosis.

Answers

Answer:

Water.

Explanation:

Cystic fibrosis may be defined as the medical condition in which the excess mucus is produced by the body that might affects the lungs and pancreas as well.

This occurs due to the abnormal functioning of chloride channel proteins. The main function of this protein is the transport of the water molecule that helps in the mucus formation. The water moves through the epithelial cells and maintain the role in epithelial fluid and fluid transport.

Thus, the answer is water.

. The Vmax of a glucose transport into a certain preparation of red blood cells is determined to be 1206nmol glucose/s without ATP present in the buffer. The Vmax of a glucose transport into the same preparation of red blood cells is determined to be 1158nmol/s when ATP is present in the buffer. However, when cells that do not express any glucose transporter are probed for rate of glucose transport, Vmax is infinite. Explain these data.

Answers

Answer:

During a process of facilitated diffusion, presence ATP increase the rate of glucose transport through a protein membrane of a red blood cells. Vmax will then be on increased.

Explanation:

The rate of glucose transport in to the certain sample of blood is a facilitated diffusion process. It is understandable to be on increase through a protein membrane with the presence of enzyme to speed up the rate of the biological reaction. This is reflected when it was initially observed that with the enzyme ATP presence in the buffer, the Vmax of a glucose transport into the certain preparation of red blood cells is determined to be 1206nmol glucose/s(considerably low).

When ATP is added, the Vmax is on increase. That is, the Vmax of a glucose transport into the same preparation of red blood cells is determined to be 1158nmol/s. Then Vmax rises to infinity, when cells that do not express any glucose transporter are probed for rate of glucose transport.

It can be further explained that glucose moves into the blood through the permease in the membrane between the cell and the blood.Thus, ATP is used as an energy source to drive Na+ out of the cell, resulting in glucose transport from the intestine to the blood.

Membrane proteins must have an asynchronous distribution on the cell membrane for the system to function. This is an example of the membrane synthetic apparatus determining where in a membrane a protein should be localized. The Na+K+ ATPase must be localized to the membrane between the cell and our blood.

The data reflects that glucose transport via GLUT1 is highly efficient and typically passive, but slightly inhibited by ATP. Without GLUT1, glucose is minimally transported across the membrane, emphasizing the necessity of transport proteins. The minor reduction in Vmax with ATP indicates possible regulatory mechanisms.

The data indicates different behaviors for glucose transport under various conditions:

Vmax of glucose transport without ATP is 1206 nmol/s, showing a high rate of passive, protein-mediated transport via GLUT1.When ATP is present, Vmax decreases slightly to 1158 nmol/s, possibly due to competition or inhibition of the transport process.Without glucose transporters, Vmax is infinite, suggesting that glucose does not pass through the membrane efficiently without these transporters, highlighting the necessity of proteins like GLUT1 for effective glucose transportation.

The data helps illustrate passive transport via GLUT1, a glucose transporter protein, and how ATP impacts the transport rate.

Why does it make biochemical sense that chaperones recognize hydrophobic surface area? What catastrophic event are chaperones meant to prevent in cells?

Answers

Answer:

Molecular chaperons in the cells helps in protein folding. These are the group of proteins that have functional similarity and they also assist protein folding.

They have the ability to prevent the non specific binding and aggregation by the binding of the non native proteins.

Molecular chaperons helps in recognizing the hydrophobic surfaces of the unfolded proteins because they themselves are hydrophobic in nature and will combine to the hydrophic binding and bonding.

This helps in guiding the protein to folding.

Final answer:

Chaperones recognize hydrophobic surface areas to prevent protein aggregation during folding, which could lead to cellular dysfunction. They help proteins fold correctly and prevent catastrophic events such as the formation of protein aggregates.

Explanation:

Chaperones recognize hydrophobic surface areas because many proteins require assistance in the folding process to prevent them from aggregating during folding. Hydrophobic regions on the protein's surface tend to be exposed and can interact with other hydrophobic regions, leading to protein aggregation. Chaperones bind to these hydrophobic regions and help the protein fold correctly by preventing aggregation. This prevents catastrophic events such as the formation of protein aggregates, which can lead to cellular dysfunction and disease.

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Imagine a genomic researcher who is analyzing the genome of different types of cats. She finds that a particular sequence in the North American Bobcat genome is exactly homologous to a sequence found in the common house cat, while all other sequences in those two genomes differ at many nucleotides. (The most recent common ancestor between bobcats and house cats is estimated to be about 6.8 million years, plenty of time for mutation to generate DNA sequence variation.)

Which of the following could explain the identical sequence in these otherwise differing genomes?

01. The sequence encodes a ribosomal protein that is critical for life and can not be easily mutated while retaining function.

02. The sequence is contained in a virus that has infected germline cells in both species.

03. The sequence is from an intron of a gene that encodes a muscle protein.

Provide a rationale for why each of the three statements above are correct or incorrect.

Answers

Answer:

Is 1. The sequence encodes a ribosomal protein that is critical for life and can not be easily mutated while retaining function.

Explanation:

"Suppose that two parents are both heterozygous for sickle cell anemia, which is an autosomal recessive disease. They have eight children. Use the binomial theorem to determine the probability that three of the children have sickle cell anemia and five of the children are healthy. Round your answer to the nearest tenth."

Answers

If two parents are both heterozygous for sickle cell anemia, the probability that three of the children have sickle cell anemia and five of the children are healthy is approximately 0.1 or 11.0%.

What is the probability of sickle cell anemia?

The probability of having 3 children with sickle cell anemia and 5 healthy children out of 8 total children is explained below.

The probability of any individual child having sickle cell anemia with heterozygous parents is 1/4; the probability of any individual child being healthy is 0.75.

Using the binomial theorem,

P(3 children with sickle cell anemia and 5 healthy children)

= [tex]P^8[/tex]₃ ×[tex](1/4)^3[/tex] ×[tex](3/4)^5[/tex]

= P(3 children with sickle cell anemia and 5 healthy children) = 0.110 that is nearly 11%.  

Hence, if two parents are both heterozygous for sickle cell anemia, the probability that three of the children have sickle cell anemia and five of the children are healthy is approximately 0.1 or 11.0%.

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Final answer:

The probability that three out of eight children of two heterozygous parents for sickle cell anemia have the disease and five are healthy is approximately 20.7%.

Explanation:

The question posed involves the application of the binomial theorem to a genetic problem involving sickle cell anemia, an autosomal recessive disease. To find the probability that three of the children have sickle cell anemia and five of the children are healthy when both parents are heterozygous for the trait, we can use the binomial probability formula:

P(X=x) = ⁿCₓ × (p)ˣ × (q)ⁿ⁻ˣ

Where 'n' is the total number of children (8), 'x' is the number of children affected with sickle cell anemia (3), 'p' is the probability of having sickle cell anemia (1/4), and 'q' is the probability of being healthy (3/4). The term 'ⁿCₓ' represents the binomial coefficient, which can be calculated using combinations.

P(3 have sickle cell) = ⁸C₃ × (1/4)³ × (3/4)⁵

Calculating further:

P(3 have sickle cell) = 56 × (1/64) × (243/1024)

P(3 have sickle cell) = 56 × (243/65536)

P(3 have sickle cell) = 13608/65536

Converting to a percentage and rounding to the nearest tenth gives us approximately:

P(3 have sickle cell) = 20.7%

Write out the form of the partial fraction decomposition of the function (See Example). Do not determine the numerical values of the coefficients. (If the partial fraction decomposition does not exist, enter DNE.) (a) x4 + 7 x5 + 5x3 A x​+ B x2​+ C x3​+ Dx+E x2+5​ (b) 2 (x2 − 9)2

Answers

Answer:

a.[tex]\frac{A}{x}+\frac{B}{x^2}+\frac{C}{x^3}+\frac{Dx+E}{x^2+5}[/tex]

b.[tex]\frac{A}{x+3}+\frac{B}{x-3}+\frac{C}{(x-3)^2}+\frac{D}{(x+3)^2}[/tex]

Explanation:

a.We are given that

[tex]\frac{x^4+7}{x^5+5x^3}[/tex]

[tex]\frac{x^4+7}{x^5+5x^3}=\frac{x^4+7}{x^3(x^2+5)}[/tex]

Using partial fraction decomposition of the given function

[tex]\frac{x^4+7}{x^3(x^2+5)}=\frac{A}{x}+\frac{B}{x^2}+\frac{C}{x^3}+\frac{Dx+E}{x^2+5}[/tex]

Using the formula

[tex]\frac{1}{x^3(x^2+a)}=\frac{A}{x}+\frac{B}{x^2}+\frac{C}{x^3}+\frac{Dx+E}{x^2+a}[/tex]

b.[tex]\frac{2}{(x^2-9)^2}[/tex]

[tex]\frac{2}{(x^2-3^2)^2}=\frac{2}{(x+3)^2(x-3)^2}[/tex]

Using property [tex]a^2-b^2=(a+b)(a-b)[/tex]

[tex]\frac{2}{(x+3)^2(x-3)^2}=\frac{A}{x+3}+\frac{B}{x-3}+\frac{C}{(x-3)^2}+\frac{D}{(x+3)^2}[/tex]

Using the property

[tex]\frac{1}{x^2}=\frac{A}{x}+\frac{B}{x^2}[/tex]

Imagine that zika virus has a 1% incidence in the population. A test for the virus has a 3% false positive rate and no false negative rate. If someone takes the test and gets a positive result, what is the chance that they are infected?

Answers

Answer:

There is 97% Chance that the person is infected.

Explanation:

According to the question, the test for the virus has 3% false positive and there is no false negative rate.

Therefore if someone takes the test and gets a positive result, the chances of the person to be infected ( True positive ) is

100 - 3 = 97%

Note: False positive result is a result that indicates that a given condition is present when it is not actually present.

"What would Avery, Macleod, and McCarty have concluded if their results had been that only RNAse treatment of the heat-killed bacteria prevented transformation of genetic virulence?

Answers

Answer:

RNA was the genetic material

Explanation:

If avary, Macleod, and McCarty would have seen that only RNAse treatment of the heat-killed bacteria prevented the transformation of genetic virulence than might have concluded that RNA is the genetic material as transformation does not occur because the RNAase degraded the RNA.

But if the genetic material is DNA then RNAase will not work because RNAase can not degrade DNA and then DNA will pass from virulent heat killed strain to nonvirulent strain and will cause transformation.

25] Discuss what your analysis above indicates about the applicability of the Hardy-Weinberg criteria to this population. Which assumptions, if any, of the Hardy-Weinberg criteria are violated

Answers

Answer: The Hardy–Weinberg principle, also known as the Hardy–Weinberg equilibrium, model, theorem, or law, states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences.

Explanation: the population is in Hardy-Weinberg equilibrium for a gene, it is not evolving, and allele frequencies will stay the same across generations. There are five basic Hardy-Weinberg assumptions: no mutation, random mating, no gene flow, infinite population size, and no selection.

The diagram shows the effect of a point mutation on a section have a gene. The nitrogenous base adenine (A) is inserted into the sequence. ( NOTE: The diagram shows the best sequence of the union the top row in the transcribe mRNA a in the bottom row) What best describes this mutation and it’s effects on the protein that the gene produces? PLEASEEEE HELPPP HURRRYYY LLEASEE

Answers

Answer: Option C) It is a frameshift mutation that changes many amino acids.

Explanation:

Due to the triplet nature of gene expression by codons, the insertion of the single Adenine nucleotide will disrupt the reading frame of the gene (frameshift mutation), such that it is no longer evenly divisible by three.

Thus, resulting in a completely different translated protein from the original.

Answer:

option c

Explanation:

because the addition of that base creates a shift in all of the rest of the bases, not just one

An individual suffers a blood clot in an artery that delivers blood to his leg. The leg begins to take on a blue hue, becomes colder than the rest of his body and he experiences numbness in the leg.
He is most likely experiencing:

a) anemic hypoxia
b) ischemic hypoxia
c) hypoxic hypoxia
d) histotoxic hypoxia
e) allergic hypoxia

Answers

Answer: Anemic hypoxia.

Explanation:

Anemic hypoxia is a medical condition that result when few haemoglobin are present in the blood leading to decreased ability of the blood to carry oxygen.

Oxygen is essential for human proper body functioning.

This is normally cause by lack of red blood cells ( haemoglobin) that carry oxygen.

The symptoms of anemic hypoxia are;

Skin color change to blue or cherry red.

Numbness

Cold hands and feet.

Headache

Weakness.

From the questions, the symptoms are similar to anemic hypoxia.

Black hair in rabbits is determined by a dominant allele, B. White hair results when a rabbit is homozygous for the recessive allele, b. Two heterozygote rabbits mate and produce a litter of three offspring.a.What is the probability that the offspring are born in the order white-black-white

Answers

Answer:

The answer if 3/64 or 4.69%

Explanation:

B-: Black; bb: white

Two heterozygote rabbits: 2^2 = 4 possible gametes.

P:         Bb          x          BbF1:      1/4 BB; 2/4 Bb; 1/4 bbthere are 3/4 black and 1/4 white

The probability that their offspring are given birth following the order white - black - white is:

1/4 white * 3/4 black * 1/4 white = 3/64 = 4.6875%

Final answer:

The probability that two heterozygous rabbits will produce offspring in the order of white-black-white is 3/64.

Explanation:

The question pertains to the probability of obtaining offspring with specific phenotypes in a certain order when two heterozygous rabbits mate. Since black hair in rabbits is determined by a dominant allele B, and white hair is the result of being homozygous for the recessive allele b, a heterozygous rabbit (Bb) can produce both black and white offspring. When two heterozygous (Bb) rabbits mate, each offspring has a 3/4 chance of being black (genotypes BB or Bb) and a 1/4 chance of being white (genotype bb).

To calculate the probability of the offspring being born in the order white-black-white, we can use the multiplication rule of independent events:

Probability of first offspring being white (bb): 1/4.

Probability of second offspring being black (BB or Bb): 3/4.

Probability of third offspring being white (bb): 1/4.

Multiplying these probabilities together:

(1/4) x (3/4) x (1/4) = 3/64

So, the probability that the offspring will be born in the order white-black-white is 3/64.

It can be desirable to produce eukaryotic proteins in prokaryotes such as E. coli. To do this several DNA sequences must be joined or cloned together. Place the labels in the appropriate position to allow for the expression of the insulin protein in a prokaryotic cell. cDNA is DNA that is synthesized from the mature mRNA from eukaryotic cells using the enzyme reverse transcriptase.

5' end_____ _____ _____ _____3' end

1. Poly A signal sequence
2. Genomic clone of insulin
3. Rho terminator
4. -95 CAT box
5. -10 TATA
6. -25 TATA box
7. cDNA of insulin
8. -35 Sequence

Answers

Final answer:

To express human insulin protein in E. coli, assemble a DNA sequence that contains a -35 Sequence, a -10 TATA box for bacterial promoter activity, followed by the cDNA of insulin, and ends with a Rho terminator for transcription termination.

Explanation:

To generate a recombinant version of the human insulin protein in a prokaryotic cell, such as E. coli, we need to assemble a proper expression cassette. The cassette needs to have a eukaryotic gene sequence converted to cDNA, combined with prokaryotic promoter and terminator sequences to allow expression in the host cell.

The correct order for cloning the insulin cDNA for expression is:

-35 Sequence-10 TATA box (also known as Pribnow box)cDNA of insulinRho terminator or a similar prokaryotic terminator

The -35 Sequence (-35 Sequence) and the -10 TATA box (-10 TATA) are part of the bacterial promoter necessary for initiating transcription. The cDNA of insulin (cDNA of insulin) is inserted downstream of the promoter, allowing it to be transcribed. Finally, a termination sequence such as the Rho terminator is necessary to stop transcription.

Why these specific elements? The -35 and -10 sequences are binding sites for the RNA polymerase in prokaryotes, which begins the process of transcription. The cDNA of insulin, obtained through reverse transcription of the mature mRNA, excludes any introns that would be present in the genomic clone (thus, we do not use the Genomic clone of insulin or the Poly A signal sequence which are found in eukaryotic expression systems). The Rho terminator is a sequence that facilitates the termination of transcription in prokaryotes.

Have your partner focus on an object on the far side of the room (e.g., the chalkboard or a chart) for 1 minute. Then have your partner switch focus to an object in your hand (e.g., a pencil). Watch your partner's pupils carefully as the point of focus is changed from far to near.

Answers

Answer:

Eye changes or adjusts itself according to the focus of our eye.

Explanation:

Pupil changes its shape when the eye focuses on near or far object. When we observe something far away, the pupil gets widen. But when we look at something near to us, pupil get smaller. So, pupil adjust itself according to the focus of our eye. If the partner switches from far to near, the pupil changes from wide to small. Pupil changes its shape according to bright as well as dim light also.

Compare the movement of nematodes (vinegar eel) with that of annelid worms (earthworm) relating these different kinds of movement to the arrangement of muscle layers in these animals. Why might peristaltic motion be considered an advancement relative to sinusiodal movement?

Answers

Answer:

they both use the muscles along side their body which moves them through the ground

Explanation:

1. Annelid worms have two layers of muscles: a layer of longitudinal muscles and a layer of circular muscles. Nematodes have a single layer of longitudinal muscles that runs the length of their body. 2. Peristaltic movement is more forceful than sinusoidal movement, allowing annelid worms to move more easily through thick or viscous materials.

1. Nematodes move through their longitudinal muscles, causing pressure throughout their bodies, and it flexes rather than flattens, moving forward with the thrust.

Circular muscles are one of annelids' three muscular layers. They are found in the outer layer of the body wall and are in charge of restricting the body. Circular muscles are necessary for locomotion, breathing, and excretion.

2. Peristaltic motion:

Furthermore, peristaltic movement permits annelid worms to travel more precisely. This is due to the ability of the longitudinal and circular muscles to be coordinated in order to produce a smooth, wave-like motion. Sinusoidal movement, on the other hand, is jer-kier.

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When Elodea cells are placed in a hypertonic solution, they lose water and their plasma membranes pull away from the cell wall. What name do we use to describe this phenomenon

Answers

Final answer:

The phenomenon observed when Elodea cells are placed in a hypertonic solution, leading to the loss of water and the plasma membrane detaching from the cell wall, is known as plasmolysis.

Explanation:

When Elodea cells are placed in a hypertonic solution, the phenomenon observed is called plasmolysis. This describes the process where the cell loses water and the plasma membrane detaches from the cell wall, resulting in the constriction of the cell membrane.

Unlike animal cells, plant cells have a rigid cell wall that prevents them from bursting in a hypotonic environment, but in a hypertonic environment, the fluid movement is out of the cell causing it to become flaccid as it loses turgor pressure. Plasmolysis can be observed in plant cells that have been underwatered and become wilted due to the absence of adequate turgor pressure to keep the cells turgid and the plant upright.

Fill in the blanks, your answers should be lower case. The process of makes an RNA copy from a DNA template. The RNA is made by the enzyme which makes the RNA from (3 or 5)' to (3 or 5)'. The process of makes a protein from an mRNA. The protein is made by the which catalyzes the peptide bond between each amino acid. In bacterial cells these two processes occur in the cytoplasm. However, in eukaryotes the process occurs in the nucleus and the process occurs in the cytoplasm

Answers

The process of transcription makes an RNA copy from a DNA template.

The RNA is made by the enzyme RNA polymerase which makes the RNA from (3 or 5)' to (3 or 5)'.

The process of  Translation makes a protein from an mRNA.

The protein is made by the peptidyl transferase in Ribosome  which catalyzes the peptide bond between each amino acid.

In bacterial cells these two processes of transcription and translation occur in the cytoplasm.

However, in eukaryotes the process of transcription occurs in the nucleus and the process of translation occurs in the cytoplasm

Explanation:

The process of translation and transcription comprises the central dogma of molecular biology. By these two process the information stored in the genes flows into the proteins.

Final answer:

The process of creating an RNA copy from a DNA template is known as transcription, conducted by the enzyme RNA polymerase. The translation of an mRNA into a protein is facilitated by the ribosome. While both processes occur in the cytoplasm in bacteria, in eukaryotes, transcription occurs in the nucleus and translation in the cytoplasm.

Explanation:

The process of transcription makes an RNA copy from a DNA template. The RNA is made by the enzyme RNA polymerase which makes the RNA from 3' to 5'. The process of translation makes a protein from an mRNA. The protein is made by the ribosome which catalyzes the peptide bond between each amino acid. In bacterial cells, these two processes occur in the cytoplasm. However, in eukaryotes, the transcription process occurs in the nucleus and the translation occurs in the cytoplasm.

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Some renewable energy resources, such as solar energy and hydropower, have several important advantages over nonrenewable resources. Which is an advantage of renewable energy resources?

Answers

Answer:

A,B,F

Explanation:

I just took the test and got it correct.

Renewable energy resources such as solar and hydropower are sustainable, enable decentralized power generation, and help in combating climate change by reducing greenhouse gas emissions.

One significant advantage of renewable energy resources such as solar energy and hydropower over nonrenewable resources is their ability to be replenished within a short timeframe. This makes them sustainable for long-term use. Solar energy, for example, is essentially inexhaustible, as it comes from the sun, which is expected to continue shining for another 4-5 billion years.

Renewable energy also facilitates local, decentralized control over power, allowing homes, businesses, and isolated communities to generate electricity with technologies such as solar panels without being dependent on a grid or centralized power plant. This is particularly beneficial for remote locations where connecting to the power grid is impractical or too expensive.

In a car accident, the injuries to the driver include a fractured femur. Part of the broken end of the diaphysis of the femur is visibly penetrating through the skin in the thigh area. Which of the following properly classifies this fracture?1. Displaced, complete, open (compound)
2. Nondisplaced, complete, open (compound)
3. Displaced, complete, closed (simple)
4. Nondisplaced, incomplete, closed (simple)
5. Displaced, incomplete, open

Answers

Answer:

1. Displaced, Complete, Open

Explanation:

Displaced fracture - in this type of bone fracture the bone breaks into two or more parts, moves and thus the parts become misaligned.

Complete fracture - in this type of fracture the parts of bone become completely separated from rest one.

Open fracture - it is compound fracture where skin breaks and part of the broken bone protrudes out of the skin.

Two strains of true-breeding maize that both produce ears of corn with white kernels are crossed and found to produce F1 plants that all make ears of corn with red kernels. If these F1 plants are backcrossed to one of the parents, what proportion of the offspring should have white kernels

Answers

Answer:

50% or 1/2

Explanation:

Since the two parental strains are true-breeding, that is, homozygous; it means that the red kerneled ears of corn offspring produced are heterozygous and one of the parental strains must have been homozygous recessive and the other homozygous dominant.

Assuming the ears of corn's colour is coded for by the allele A, it means that one of the parents has the genotype AA while the other has aa with the offspring having genotype Aa.

AA and aa genotypes produce white ears of corn while Aa genotype produce red ears of corn.

Thus, if Aa is backrossed to either of AA and aa:

Aa  x  AA = AA (white), AA (white), Aa (red) and Aa (red)

Aa x aa = Aa (red), Aa (red), aa (white) and aa (white)

Hence, the proportion of the offspring with white kernels will be 50% in each case.

Along with a balanced diet, weight-bearing exercise promotes bone mineral density. Ruben's body-builder diet would be unhealthy for his bones over the long term because it is __________.

Answers

Answer: it is lacking adequate levels of Vitamin D and Calcium.

Explanation:Vitamin D deficiency can lead to loss of bone density, which is a contributory factor to osteoporosis and broken bones.

Severe vitamin D deficiency can also lead to other diseases. Vitamin D deficiency leads to osteomalacia. Osteomalacia which causes weak bones, bone pain, and muscle weakness. Because Reuben's body builder diet lacks Vitamin D, it can cause fractures and even osteoporosis over when used for a long time especially without trying to make amends for the deficient Vitamin D.

Answer:inadequate in vitamin D and excessive in calcium

Explanation:

Vitamin D plays a significant role in the regulation of calcium and maintenance of phosphorus levels in the blood. These factors are vital for maintaining healthy bones. People need vitamin D to allow the intestines to stimulate and absorb calcium and reclaim calcium that the kidneys would otherwise excrete.

Foods that provide vitamin D include:fatty fish, like tuna, mackerel, and salmon.

Foods fortified with vitamin D, like some dairy products, orange juice, soy milk, and cereals.

Beef liver.

Cheese.

Egg yolks.

what color would the ecoli cell appear under the microscope following a gram stain? explain why with a clear explanation of the gram staining process and the peritnent cellular componests that cause cells to stain

Answers

Answer:E. Coli will appear pink in color under the microscope following gram staining

Explanation:

The Gram stain is a differential technique that is commonly used for the purposes of classifying bacteria. The staining technique distinguishes between two main types of bacteria (gram positive and gram negative) by imparting color on the cells.

Being Gram-negative bacteria, E. coli have an additional outer membrane that is composed of phospholipids and lipopolysaccharides. The presence lipopolysaccharides on the outer membrane of bacteria gives it an overall negative charge to the cell wall. Because of these properties, E. coli does not retain crystal violet during the Gram staining process.

You purchase two identical houseplants and place them side by side on your windowsill. You water both plants equally. One plant, plant a, you leave alone. On the other plant, plant b, you inject florigen into the cells of the apical meristem. Which of the following would you expect to occur? (Select all answer options that apply.)
a. While flowering, the leaves will stop growing on plant b because florigen inhibits leaf meristems.
b. In subsequent years, plant b will only generate flowers in the same place.
c. Plant b will produce a flower at its apical meristem.
d. Once the flower is gone, plant b will grow taller, but only from growth of lateral meristems.
e. Both plants will produce flowers at the same time, but plant b will have more of them.
f. Once the flower is gone, the apical meristem will develop again, and plant b will continue to grow from that stem.

Answers

Answer: Option E.

Both plants will produce flower at the same time but plant B will have more of them.

Explanation:

Florigen is a protein or hormone like molecule that help to control or boost flower production in plants. It is a flowering hormone. It is produced in plants leaves and acts on apical meristem or growing tips. The hormone is normally injected at the growing tips or apical meristem where flowers growth will be activated. Since plant B is injected with florigen,it will further trigger flower production on the plant than plant A .

Answer: C

Explanation:

The blood of a normal healthy adult rat contains 5 million red blood cells (RBCs) per microliter of blood. Each deciliter of blood contains 15 grams of hemoglobin. Each RBC contains 250 million molecules of hemoglobin (a fairly close approximation for a healthy adult retired breeder female rat). Suppose you have 8.56 mL of blood drawn from a healthy female retired breeder rat, then how many RBCs are in this blood sample?

Answers

Answer:

There are 4.28×10^10 RBCs in the blood sample.

Explanation:

Concentration of blood = 5×10^6 RBC/10^-6 L = 5×10^12 RBC/L of blood

Volume of blood sample = 8.56 mL = 8.56/1000 = 0.00856 L

Number of RBCs = concentration of blood × volume of blood sample = 5×10^12 RBC/L × 0.00856 L = 4.28×10^10 RBCs

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